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Emergent Technologies has acquired extensive experience and expertise in the evolving carbohydrate
research development field over the past 5 years. Emergent Technologies currently manages and
directs a unique group of glycosaminoglycan portfolio companies. Collectively Emergent
Technologies and its portfolio companies have over 15 patents covering unique synthesis
techniques for carbohydrate compounds such as heparin, chondroitin, hyaluronic acid and
associated chimeric derivatives.
Emergent Technologies leverages this expertise across
multiple industrial and general consumer application arenas and is positioned
to serve as an international carbohydrate innovation clearinghouse.
Dr. Paul L. DeAngelis serves as the Chief Scientific
Officer of Heparinex. Dr. DeAngelis is
a recognized leader in the glycobiology field and has been directly involved in
commercializing technologies associated with heparin, chondroitin, and
hylaronic acid developed in his laboratories.
Carbohydrate Expertise: Paul L. DeAngelis has explored glycobiology throughout his career.
As an undergraduate at Harvard (B.A. 1984), Dr. DeAngelis investigated the carbohydrate structures
of polysaccharides from fungal pathogens that their plant hosts detected as "foreign" by creating and
testing a series of synthetic structural mimics. As a graduate student at the University of California,
Irvine (Ph.D. 1990), he elucidated unique details surrounding fertilization, such as defining the critical
elements of egg surface polysaccharides and the essential residues of a sperm adhesive protein.
As a postdoctoral researcher (1990-93) in the laboratory of Dr. Paul Weigel at the University of
Texas Medical Branch, Galveston, Dr. DeAngelis identified the first hyaluronan synthase to be
described from the human bacterial pathogen Group A Streptococcus. Currently, as an Associate
Professor at the University of Oklahoma Health Sciences Center in Oklahoma City, he directs a
laboratory exploring various aspects of prokaryotic and eukaryotic polysaccharide biosynthesis.
Discoveries from 1997 to 2003 include the identification of two more unique hyaluronan synthases
and the first chondroitin and heparin synthase.
For more information visit the following link: http://w3.ouhsc.edu/biochem/DeAngelis.htm
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